News & Events

Bascom Palmer Researcher Identifies New Genetic Mutation in Ocular Melanoma

University of Miami Miller School of Medicine, January 24, 2014 | Bascom Palmer Eye Institute ophthalmologist J. William Harbour, M.D., has identified a new genetic marker for determining the virulence of ocular melanomas in a groundbreaking study published online January 13 in the prestigious journal Nature Genetics. “Our research team discovered that the RNA splicing factor SF3B1 is mutated at a very specific location in some ocular melanomas, and this mutation indicates the likelihood that an ocular melanoma will metastasize and spread to other parts of the body, a ... Read More

Enabling Personalized Medicine in the Management of Uveal Melanoma

In the November/December edition of Retina Today, retina specialist Thomas Aaberg Jr. describes the importance of personalized medicine and prognostic testing for patients with uveal melanoma. He explains that recent advances in the field have led to more than 40 active clinical trials testing ways to treat and delay metastatic disease. However, taking advantage of these and future opportunities may require genetic testing of the primary tumor. This presents a significant issue since there is rarely any ... Read More

Castle Biosciences Launches Tissue Repository for Eye Cancer Patients

Patients Undergoing Genetic Test for Uveal Melanoma Will Have Option to Store Remaining Tissue for Future Use Castle Biosciences News Release 9/30/13 – Castle Biosciences Inc. announced today the availability of a tumor tissue repository for patients whose tumors are being tested with the Company’s gene test for uveal, or ocular, melanoma. Patients will now have the option of storing an additional sample of their tumor free of charge for up to five years, and ... Read More

Drug Is A First To Help Patients With Melanoma Of The Eye

By Julie Steenhuysen, Reuters, June 1, 2013 | In his first few weeks as head of the melanoma group at Memorial Sloan-Kettering Cancer Center seven years ago, a young man walked into Dr. Gary Schwartz’s office with a rare form of the skin cancer that affects the eye. “It was horrible. He died of metastatic disease. He was only 24. I promised him I would find a way to cure his cancer,” recalls the physician-scientist of the patient who helped inspire his quest ... Read More

PLOS Currents Confirms DecisionDx-UM Accuracy and Clinical Use

In the online journal PLOS Currents: Evidence on Genomic Tests, the DecisionDx-UM molecular test was cited as the most accurate prognostic factor for individualizing care for uveal melanoma patients. “… the DecisionDx-UM gene expression profile test is a stand-alone platform which requires no other information for maximal prognostic accuracy and which circumvents many of the drawbacks of chromosomal methods…” DecisionDx-UM groups patients into high- and low-risk categories and is being used to better determine follow-up care. ... Read More

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Know your TYPE, Know your RISK
You’ve just been diagnosed with uveal melanoma, and it’s important to know that there is a test that can identify your tumor type—and the risk of your cancer spreading.

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GETTING TESTED       Timing is Critical
To know your tumor type and risk, a biopsy must be taken BEFORE radiation treatment.

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Talk to                 Your Doctor
Use this discussion guide to talk to your doctor about the genomic test to learn your tumor type, or CLASS.

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