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Study Results with Castle Biosciences’ Uveal Melanoma Gene Expression Test Published in Journal of Oncology

Friendswood, TX—August 10, 2016—Castle Biosciences, Inc., a provider of molecular diagnostics to improve cancer treatment decisions, today announced the publication of clinical data on DecisionDx®-UM, its gene expression profile (GEP) test to predict metastasis in patients diagnosed with uveal melanoma (UM). The paper, “Clinical Performance and Management Outcomes with the DecisionDx-UM Gene Expression Profile Test in a Prospective Multicenter Study” was recently published in the Journal of Oncology. The prospective, multicenter CLEAR (Clinical Application of ... Read More

Castle Biosciences Announces New Clinical Data to be Presented at ASCO 2016 Confirming Performance of DecisionDx-UM Gene Expression Profile (GEP) Test in Uveal Melanoma

Friendswood, TX—May 19, 2016—Castle Biosciences, Inc., a provider of molecular diagnostics to improve cancer treatment decisions, today announced new clinical data on DecisionDx®-UM, its gene expression profile (GEP) test to predict metastasis in patients diagnosed with uveal melanoma. The new data will be highlighted in a presentation at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting being held in Chicago, IL from June 3-7. In a poster presentation titled, “A Prospective, Multi-Center Study ... Read More

Study Shows Castle Biosciences’ DecisionDx-UM is Highly Effective at Predicting Metastatic Risk in Patients with Eye Cancer

Results presented at the ASOPRS 46th Annual Fall Scientific Symposium Friendswood, TX – November 16, 2015 – Castle Biosciences, Inc., a provider of molecular diagnostics to improve cancer treatment decisions, today announced new study results of the Company’s DecisionDx-UM gene expression profile test, verifying that the assay is highly effective at identifying uveal melanoma tumors at high risk of metastasis. The results also confirmed the technical reliability of the test, which successfully classified 97% of ... Read More

Vast Majority of Ophthalmologists Treating Uveal Melanoma Use Molecular Testing to Guide Patient Care

Castle Biosciences News Release 12/9/14 | Castle Biosciences Inc. today announced the publication of study results that assess current clinical practices for uveal melanoma (UM) and demonstrate the impact of molecular prognostic testing on patient management. The paper, “Current clinical practice: differential management of uveal melanoma in the era of molecular tumor analyses,” was published in the peer-reviewed journal Clinical Ophthalmology. The publication presents results from three studies: a survey of 109 ophthalmologists specializing in the treatment of uveal melanoma conducted ... Read More

Bascom Palmer Researcher Identifies New Genetic Mutation in Ocular Melanoma

University of Miami Miller School of Medicine, January 24, 2014 | Bascom Palmer Eye Institute ophthalmologist J. William Harbour, M.D., has identified a new genetic marker for determining the virulence of ocular melanomas in a groundbreaking study published online January 13 in the prestigious journal Nature Genetics. “Our research team discovered that the RNA splicing factor SF3B1 is mutated at a very specific location in some ocular melanomas, and this mutation indicates the likelihood that an ocular melanoma will metastasize and spread to other parts of the body, a ... Read More

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Know your TYPE, Know your RISK
You’ve just been diagnosed with uveal melanoma, and it’s important to know that there is a test that can identify your tumor type—and the risk of your cancer spreading.

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GETTING TESTED       Timing is Critical
To know your tumor type and risk, a biopsy must be taken BEFORE radiation treatment.

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Talk to                 Your Doctor
Use this discussion guide to talk to your doctor about the genomic test to learn your tumor type, or CLASS.

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